We raise the bar for professionals by creating powerful products. We took a new approach to the idea of a well-developed T-booster, a preparation which has a positive influence on the actual level of free testosterone in the body, and chose tried, synergistic solutions enhanced with the newest active substances. This mechanism is based not only on increasing the testosterone production alone, but also on raising the amount of its free form in the bloodstream to the maximum as well. That is how we created the composition of the two active ingredients combined in two formulas: TESTO-GENERATION and PRO Activation Blend.
The most innovative substance used in TESTOXEED is the patented, standardized ashwagandha root extract (KSM-66).
The specialists from Ixoreal Biomed required 14 years (1) to develop the process of extraction, but they have finally found the ideal way.
KSM-66 – increases the level of LH and testosterone, and improves semen
Research (2) proves that KSM-66 helps treat infertility and has a positive influence on the hormonal profile of the male body. After 90 days of taking 675mg of KSM-66 three times a day, the volunteers were examined with regard to the parameters of their semen and the level of hormones in the serum. In the group taking KSM-66 the level of hormones improved: the level of testosterone grew by 17%, and the level of the luteinizing hormone (LH) by 35% (fig. 1, 2). LH is responsible for the proper functioning of the interstitial cells of Leydig that produce testosterone in men. Moreover, the group taking KSM-66 displayed a 167% increase in the amount of spermatozoons in the semen, a 53% increase in the semen volume, and a 57% increase in the spermatozoons’ mobility. In the placebo group, the improvement of these parameters was minimal.
Fig. 1 Testosterone level in the serum in the group taking KSM-66 or placebo at the beginning and at the end of the trial.
Fig. 2 Luteinizing hormone (LH) level in the serum in the group taking KSM-66 or placebo at the beginning and at the end of the trial.
KSM-66 – increases lean body mass and accelerates post-exercise regeneration
The effectiveness of KSM-66 in this aspect was studied in a randomized double-blind placebo-controlled trial whose participants were 50 young men who regularly did strength exercises (3). They were divided into two groups. The first group (n=25) took a placebo, while the other group (n=25) took 300mg of KSM-66 two times a day for eight weeks.
Taking KSM-66 significantly improved the strength and size of the muscles, and decreased the amount of fat tissue (Fig. 3, 4, 5), it also accelerated the rate of post-exercise regeneration assessed on the basis of the decrease in the level of creatine kinase (CK) in the bloodstream – an enzyme found in the muscles whose level in the bloodstream rises during illnesses related to muscle damage.
Fig. 3 Comparison of muscle strength assessed on the basis of one repetition on a flat bench with a maximum load in the placebo group and in the group taking KSM-66 in the 8th week of the trial.
Fig. 4 Shoulder muscle size (cm2) in the placebo group and in the group taking KSM-66 in the 8th week of the trial.
Fig. 5 Fat tissue reduction in % in the placebo group and in the group taking KSM-66 in the 8th week of the trial.
KSM-66 – lowers cortisol and stress levels
A randomized, double-blind, placebo-controlled trial on 64 people showed that KSM-66 safely and effectively improves resistance to stress, and thus increases one’s quality of life. The effectiveness of use for KSM-66 was conducted after 60 days of supplementation with 300mg amounts taken two times a day (4).
The supplementation with KSM-66 for 60 days caused a 44% reduction in the level of stress assessed with the use of the PSS (Perceived Stress Scale) questionnaire and the reduced number of points obtained in the GHQ-28 test, which is proof of the improvement of psychological health. The final questionnaire was the DASS questionnaire, namely the scale of depression, anxiety, and stress. In the group taking KSM-66 the results obtained for each of these components showed a reduction.
The influence of KSM-66 on the level of cortisol was also studied. The two groups had a similar initial level of cortisol. After 60 days of taking KSM-66, the reduction of cortisol was 27.9% in one group, while in the placebo group the reduction was only 7.9% 4 (Fig. 6).
TESTOXEED – TESTO-GENERATION:
DAA – clinically tested D-aspartic acid which naturally occurs in our endocrine cells, adrenal glands, pancreas, thyroid, parathyroid and largely in the pituitary gland and testes. The participation of DAA in the mechanisms regulating testosterone production supporting the development of muscle mass has been described only in recent years. It was observed that that D-aspartic acid releases GnRH from: the hypothalamus, the luteinising hormone (LH) and growth hormone (GH) from the pituitary gland, and testosterone from the testes(5).
In 2009 studies were conducted(6) which analysed the impact of DAA (3.12 g/day) on the levels of testosterone and LH in healthy men. The experiment lasted 12 days and clearly depicted the effectiveness of the analysed DAA. The level of testosterone increased by 43% and LH by 33%. Moreover, elevated LH and testosterone levels were observed even after ceasing supplementation with D-aspartic acid (see the table below). In the placebo group, there were no significant changes.
Such prominent effects were achieved with a DAA daily dose of 3.12 g. Olimp Sport Nutrition® went a step further by offering a daily dose of 3200 mg of pharmaceutical grade DAA to a group of the most demanding people striving to improve the quantity and quality of muscle mass as well as physical performance.
||AFTER 6 DAYS OF TAKING
||AFTER 12 DAYS OF TAKING
||3 DAYS AFTER CEASING SUPPLEMENTATION
|LH (mIU/ml serum)|
|Persons taking DAA
||4,2 ± 0,5||4.5 ± 0,6||5.6 ± 0,9||4,8 ± 0,8|
|Persons taking placebo
||4,2 ± 0,4||4,3 ± 0,7||4,2 ± 0,6||4,1 ± 0,5|
|TESTOSTERON (ng/ml serum)|
|Persons taking DAA
||4,5 ± 0,6||5,2 ± 0,7||6,4 ± 0,8||5,8 ± 0,6|
|Persons taking placebo
||4,6 ± 0,5||4,5 ± 0,7||4,7 ± 0,7||4,6 ± 0,7|
Common oat extract, standardized to contain 7% flavonoids.
Scientific reports (7) convince us that flavones have the strongest effect of all plant flavonoids in terms of inhibiting aromatase activity. Lowering the activity of this enzyme allows men to avoid the unpleasant consequences of increased estrogen levels in their bodies, this is especially useful for people who are susceptible to developing such conditions which can result in gynecomastia, i.e. the accumulation of fat around the abdomen and thighs, excessive accumulation of water in the body, and sexual dysfunctions. Other research prove that substances contained in oats simultaneously increase testosterone production(8). Additionally, it contributes to an overall strengthening of the body including an increase in physical capabilities, and it intensifies the resistance to psychological weariness.
Trans-resveratrol – contained in grape-skin extract helps maintain the proper functioning of the circulatory system. It slows down the ageing process, currently it is considered to be the best “anti-ageing” anti-oxidant in the world, it strengthens the nervous and immunological systems, improves the endothelium of blood vessels by increasing their elasticity, prevents the development of inflammation in the vessels thus preventing the formation of atherosclerosis, minimizes the unwanted effects of estradiol (shows aromatase inhibitor activity), inhibits the rate of the breakdown of collagen in the skin, tendons, and the ligaments in the joints, and has a positive influence on the regeneration of joints. In order to take advantage of the entire potential of this compound it should be taken together with other flavonoids that increase its bioavailability and its activity level.
Maca root and fenugreek extract – the first of these substances helps maintain natural sexual activity and energy, and it supports physical and mental activity. To complement these properties, we added fenugreek extract which contains active substances known for their anti-oxidizing properties that support the immunological system.
Zinc (amino acid chelate Albion®) – zinc is necessary for the proper synthesis of protein and proper division of cells. Additionally, it helps to maintain the proper testosterone level in the bloodstream, and helps maintain the proper fertility and reproductive functions.
TESTOXEED – PRO Activation Blend:
Roseroot extract has adaptogenic properties protecting the body during physical activity by tackling the feeling of weariness, increasing the physical efficiency of the body, increasing the resistance to mental and physical stress, and additionally stimulating the nervous system which improves one’s mental state.
AstraGin™ (a patented mixture of extracts: Panax notoginseng and Astragalus membranaceous) – and optimises the rate of absorption and the metabolism of nutritional macrosubstances.
Five-flavour berry extract – improves the body’s ability to withstand stress, and thus helps maintain the inner homeostasis of the body. It also serves as an excellent anti-oxidant, effectively lowering the level of free radicals.
Black pepper extract standardized to contain 95% piperine – has significant anti-oxidizing properties, and thanks to its antibacterial and anti-inflammatory properties it support the immunological system.
TIME TO GET TESTOXEED –the new weapon in the battle to increase your TESTOSTERONE level!
2) Ambiye VR, Langade D, Dongre S, et al., Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study. Evid Based Complement Alternat Med. 2013;2013:571420.
3) Wankhede Sachin, Effects of Ashwagandha Root Extract (Withania somnifera) on Muscle Strength, Size and Recovery, Testosterone, and Body Fat in Healthy Adults, Sports Medicine and Doctors Fitness Zone, Pune India.
4) K. Chandrasekhar, Jyoti Kapoor, Sridhar Anishetty, A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults, Indian J Psychol Med. 2012 Jul-Sep; 34(3): 255-262.
5) D’Aniello A, et al. Occurrence of D-aspartic acid and N-methyl-D-aspartic acid in rat neuroendocrine tissues and their role in the modulation of luteinizing hormone and growth hormone release. FASEB J. 2000 Apr;14(5):699-714.
6) Topo E, et al. The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats. Reprod Biol Endocrinol. 2009 Oct 27;7:120.
7) Li et al., Dietary flavones and flavonones display differential effects on aromatase (CYP19) transcription in the breast cancer cells MCF-7. Mol Cell Endocrinol. 2011 Sep 15;344(1-2):51-8.
8) Janeczko Z.: Zastosowanie owsa zwyczajnego (Avena sativa L.) w terapii i kosmetyce. Farmacja Polska 2003, 59, 846
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.